The Australian Brain Bee Challenge is an annual competition for students in Year 10 (AUS) to learn about the brain and its functions, learn about neuroscience research, find out about careers in neuroscience and to dispel misconceptions about neurological and mental illnesses.

The program was started in Australia in 2006 to address a number of deficiencies in the public's perception of science in general, and neuroscience in particular.

The Brain Bee Challenge provides current and accurate information on the latest advances in neuroscience research, its value to the community, and promote careers in science and technology.

This event is free, and is funded by the Australasian Neuroscience Society. Winners of Round 1 progress to further rounds of the Brain Bee Challenge, culminating in the International Brain Bee World Championships.