University of Auckland

Aotearoa Post-Doctoral Research Fellow

The Opportunity

We seek a candidate who has completed a PhD or equivalent postgraduate research degree and has up to six years of active postdoctoral research experience. These fellowships are usually awarded to candidates with three to six years of experience, but in exceptional circumstances we will consider recently qualified candidates with a stellar record or those with more than six years of postdoctoral experience.

This prestigious personal award is a Post-doctoral Fellowship funded by the Aotearoa Foundation to recognise an outstanding emerging scientist who has shown the potential to be a research leader of the highest international calibre. The fellowship will assist them to develop an independent research programme and develop a career as a future research leader.

Research projects are available in any area of neuroscience aligned with the CBR's research themes. Before applying applicants should contact a CBR principal investigator (https://www.fmhs.auckland.ac.nz/en/faculty/cbr/our-research/research-teams.html) to discuss the proposed research project and gain their endorsement.

Fellowship purpose:

This Fellowship is one of a number funded by the Aotearoa Foundation to enable an outstanding emerging Scientist to develop an independent research programme at the University of Auckland and as a future research leader. We are especially interested in applicants whose work will facilitate the centre's strategic goals (https://www.fmhs.auckland.ac.nz/en/faculty/cbr/our-centre/our-vision.html), and which bridge clinical and biomedical research spheres. The Post-Doctoral Fellow is expected to develop research leadership skills and research independence during the fellowship and the centre provides opportunities to assist in developing these skills.

Who are we?

The University of Auckland is New Zealand's leading University, with a turnover of $1.1bn, including research revenue of over $200m generated across eight diverse faculties and two research institutes. We employ more than 5400 academic and professional staff to support over 41,000 students, making us one of NZ's largest employers.

The Centre for Brain Research fosters neuroscience research through a collaboration across the entire University of Auckland. Scientists, Doctors and students work at every level; from the laboratory to the clinic to the whānau and the community, enabling us to provide novel insights on how the brain stimulates, controls and interacts with the rest of the body. Details of the core research activities, projects and strategic objectives of the CBR are available on the website:https://www.fmhs.auckland.ac.nz/en/faculty/cbr/our-centre.html

Why work for us?

The University of Auckland is committed to providing an excellent working environment through:

* flexible employment practices

* career development programmes

* a competitive salary with five weeks' annual leave

* a company superannuation scheme, discounted car parking, a generous parental leave allowance, childcare and a number of other discounts on internal and external services.

Applications close 29 March 2019

For further information and to apply online please visit www.auckland.ac.nz/opportunities

The University is committed to meeting its obligations under the Treaty of Waitangi and achieving equity outcomes for staff and students in a safe, inclusive and equitable environment. For further information on services for Maori, Pacific, women, LGBTI, equity groups, parenting support and flexible work go to www.equity.auckland.ac.nz

Direct enquiries only please - no agencies.

 

Research Fellow (PET and PET/MR Neuroimaging Post-Doc)

Job No.: 586930
Location: Clayton campus
Employment Type: Full-time
Duration: 2 year fixed-term appointment
Remuneration: $68,040 - $92,343 pa Level A (plus 9.5% employer superannuation)

• Be inspired, every day
• Drive your own learning at one of the world’s top 80 universities
• Take your career in exciting, rewarding directions

Everyone needs a platform to launch a satisfying career. At Monash, we give you the space and support to take your career in all kinds of exciting new directions. You’ll have access to quality research, infrastructure and learning facilities, opportunities to collaborate internationally, as well as the grants you’ll need to publish your work. We’re a university full of energetic and enthusiastic minds, driven to challenge what’s expected, expand what we know, and learn from other inspiring, empowering thinkers.

The Opportunity

The Monash Institute of Cognitive and Clinical Neurosciences (MICCN: housed within the School of Psychological Sciences) is looking to appoint a Research Fellow (PET and PET/MR Neuroimaging Post-Doc) who will focus on investigating mechanisms of neurodegeneration in the human brain using Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI).
This position will also include implementing and validating experimental scanning protocols, managing and undertaking statistical analysis of the imaging and behavioural data, performing appropriate theoretical and computational modelling, and providing reports of the measurements and results.


Data acquisition and analysis will focus on brain Positron Emission Tomography (PET) using novel investigational tracers in individuals with genetically-determined neurodegenerative diseases, including Huntington’s disease and Friedreich ataxia. Secondary comparisons with MRI measures of neurodegeneration will be undertaken, exploiting multi-modal data acquired using the MR-PET scanner and associated technologies located at Monash Biomedical Imaging (MBI).


To be successful in the role, you will have a doctoral qualification in neuroscience or computational discipline with demonstrated expertise in Positron Emission Tomography (PET). Familiarity and/or expertise with Magnetic Resonance Imaging (MRI) modalities, or other relevant disciplines, will be considered a strong asset.
This role is a full-time position; however, flexible working arrangements may be negotiated.
At Monash University, we are committed to being a Child Safe organisation. Some positions at the University will require the incumbent to hold a valid Working with Children Check.

Your application must address the selection criteria. Please refer to "How to apply for Monash jobs". Please click here for more details. 

Enquiries

Dr Ian Harding, Research Fellow, Monash Institute of Cognitive and Clinical Neurosciences, +61 3 9903 9283
Position Description: Research Fellow (PET and PET MR Neuroimaging Post-Doc)

Applications Close Monday 8 April 2019, 11:55 pm AEDT

 

Postgraduate Research Stipend to develop cannabinoids as potential therapeutics to treat myasthenia gravis

This Scholarship will provide a stipend towards the living expenses of a PhD student to learn to use intracellular electrophysiological recordings to develop cannabinoid compounds as potential new drugs to restore synaptic function in mouse models of myasthenia gravis.

Location:

Discipline of Physiology, Faculty of Medicine, Sydney Medical School

http://sydney.edu.au/medicine/physiology

Supervisors: A/Prof William Phillips (Physiology) and A/Prof Stephen Reddel (Medicine, Neurology) University of Sydney.

Synopsis

Myasthenia gravis is a serious paralysing disease caused by failure of synaptic transmission at the neuromuscular junction. New treatments to improve synaptic function are needed, current treatments largely require immunosuppression with substantial risks and limitations.

This Scholarship is available for a PhD student to undertake a project using intracellular electrophysiological recordings to develop and test cannabinoid-like compounds as potential future drugs to treat diseases of the neuromuscular synapse.

The project will build upon recent work of the supervisors (Morsch, Protti, Cheng, Braet, Chung, Reddel & Phillips. 2018. Sci Rep 8, 4685). This exciting study shows that cannabinoids change a fundamental property of synaptic transmission – that the size of the released transmitter quanta, which the name would suggest are meant to be of fixed size – are in fact malleable and altered by cannabinoids, with rapid effects on post synaptic transmission amplitudes. This suggests that cannabinoids could provide rapid benefit without immunosuppression. As the neuromuscular junctions are outside the CNS, peripherally restricted therapeutic cannabinoids could be developed without CNS toxicity.

The candidate will be based in the Discipline of Physiology, University of Sydney. Collaboration will be with the Lambert Initiative, University of Sydney ( https://sydney.edu.au/lambert/) including development of peripherally restricted cannabinoids for testing in this project. The scholarship will help support the living costs of the student while they complete their studies.

Keywords

neurology, neuroimmunology, synapse, neuromuscular junction, acetylcholine, AChR, MuSK, muscle specific tyrosine kinase, myasthenia gravis, neuromuscular disease, muscle, electrophysiology, single fibre, intracellular, electrode, cannabinoid, cannabinoid receptor, lambert initiative,

Other Information

The candidate will learn to master intracellular electrophysiology and pharmacology.
An experienced electrophysiologist will train you during 2019.
Applicants must hold an Honours degree (First Class) or a Master's degree in a related field with a substantial research component, or equivalent such as a medical degree with Honours.
This Stipend Scholarship will provide an annual stipend allowance equivalent to the minimum RTP rate. The recipient may apply for an extension of up to 6 months.
The Scholarship is for commencement by mid 2019 and cannot be deferred or transferred to another area of research.


To apply please email a cover letter indicating why you are interested in the project and attach a copy of your current cv to Bill Phillips (This email address is being protected from spambots. You need JavaScript enabled to view it.) and Stephen Reddel (This email address is being protected from spambots. You need JavaScript enabled to view it.).